Which option is the first-line treatment for laryngeal cancer?

• A. Chemotherapy
• B. Surgery
• C. Radiation therapy
• D. Immunotherapy

Answer: (B)

The main idea is that achieving control of the tumor while preserving laryngeal function guides initial treatment choices. For many early-stage laryngeal cancers, removing the tumor surgically using a voice-preserving approach (such as a partial laryngectomy or transoral laser resection) is a common first-line option because it provides immediate tumor clearance, allows precise assessment of margins, and often yields good preservation of voice and airway function. Radiation therapy is also effective and widely used, especially for organ preservation, but in many exam contexts the upfront surgical approach is considered the initial standard when feasible. Chemotherapy is typically reserved for larger or more advanced disease or used in combination with radiation (chemoradiation) for organ preservation, and immunotherapy is generally for recurrent or metastatic settings or clinical trials.